The -15℃ constant-temperature crystallization process support in chemical reaction vessels by low temperature chiller is completely feasible and has been widely verified in multiple industries and practical applications.

I. Technical Capabilities and Application Scope of low temperature chiller

low temperature chiller is mainly used in chemical reaction vessels to provide stable low-temperature cooling water to achieve precise temperature control of the reaction process. According to multiple sources, the temperature control range of low temperature chiller is wide, capable of meeting different requirements from -100℃ to +250℃. For instance, the KANSJIE brand's dual-purpose cold and hot water chiller can offer a temperature range from -100℃ to +250℃, making it suitable for temperature control in reaction vessels in industries such as chemical engineering and pharmaceuticals. The LC series low temperature chiller of Wuxi Guanya Refrigeration Technology Co., Ltd. achieves continuous temperature control from -90°C to +250°C and has high-precision linear control capability.

For the constant-temperature crystallization process at -15℃, low temperature chiller is fully capable of meeting the requirements. For instance, the KDS-260DLB integrated low-temperature water-cooled screw chiller provided by Kaideli Company has a minimum coolant outlet temperature of -20℃, which can meet the requirements of low-temperature environments in chemical production lines. In addition, the chiller for reaction vessels produced by Nanjing Bok Company also supports a temperature adjustment range of chilled water from -35℃ to +5℃, which is suitable for cooling and cooling of chemical reaction vessels.

Ii. Application of low temperature chiller in Crystallization Process

The application of low temperature chiller in the crystallization process is particularly crucial. The crystallization process usually requires strict temperature control to ensure the purity and morphology of the crystals. For instance, in the synthesis of pharmaceutical intermediates, the Grignard reaction is often carried out at -20℃, with a gradient cooling of 2℃/min achieved through PID control. In the preparation of polymers, a 100L glass reactor needs to provide an environment of -80℃ to control the polymerization rate of acrylate monomers.

For the constant-temperature crystallization process at -15℃, low temperature chiller can stabilize the temperature inside the jacket of the reaction vessel at the target value through the circulating cooling water system. For instance, the GR series double-layer glass crystallization kettles provided by Shanghai Boyan Constant Temperature Equipment Co., Ltd. can be used within the range of -120℃ to 200℃, support heating and low-temperature reactions, and are suitable for fields such as medicine, chemical engineering, and biology. In addition, the HJL-070WL low-temperature series screw chiller of Wuhan Huajuleng Refrigeration & Electrical Machinery Co., Ltd. is also specifically designed for the crystallization cooling of chemical reaction vessels.

Iii. Application Cases of low temperature chiller in Actual Projects

Several practical projects have verified the application effect of low temperature chiller in chemical reaction vessels. For instance, Zhangjiagang Diaisheng Chemical Co., Ltd. has adopted water-cooled screw chillers in its resin production facilities, with refrigerants R22 and R407C, which meet the low-temperature cooling requirements of the reaction vessels and condensers. In addition, Kaideli Company customized an integrated low-temperature water-cooled screw chiller for a certain client. The minimum outlet temperature of the refrigerant can reach -20℃, which can meet the high requirements for low-temperature environments in chemical production lines.

In the application of industrial low temperature chiller at minus 10 degrees, studies have shown that this equipment can provide stable low-temperature conditions for chemical crystallization reactions, improving the purity and yield of compounds. In addition, low temperature chiller can also use ethylene glycol as the heat transfer medium to provide coolant ranging from -5 ° C to -35 ° C, which is suitable for production requirements in low-temperature and low-humidity environments.

Iv. Advantages and Technical Features of low temperature chiller

The application of low temperature chiller in chemical reaction vessels has the following advantages:

1. High-precision temperature control: low temperature chiller can achieve a temperature control accuracy of ±0.2℃ to ±2℃, ensuring the stability of the reaction process.

2. High efficiency and energy saving: low temperature chiller adopts advanced refrigeration technologies, such as single-machine cascade refrigeration technology, which can achieve efficient cooling effects with relatively low energy consumption.

3. Safety and reliability: low temperature chiller is equipped with multiple protection devices, such as phase sequence protection, motor overload protection, anti-freezing protection, etc., to ensure the safe operation of the equipment.

4. Flexible and adjustable: low temperature chiller can flexibly adjust the temperature and flow rate according to different process requirements to meet the cooling needs of different reaction stages.

V. Conclusion

To sum up, the support of the -15℃ constant-temperature crystallization process in the chemical reactor by low temperature chiller is completely feasible. Through precise temperature control and efficient cooling capacity, low temperature chiller can provide a stable low-temperature environment for chemical reactions, improving product quality and production efficiency. Whether it is single-machine cascade refrigeration technology or multi-stage cooling system, low temperature chiller can meet the cooling requirements under different process conditions. Therefore, low temperature chiller is an ideal choice for realizing the constant-temperature crystallization process of -15℃ in chemical reaction vessels.